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CBD Research Archive

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This CBD Research Archive is sorted by possible health benefits. These are not all of the studies available. This list is intended to help people find this information in one place. The best tool any industry has is education. Helping consumers make educated decisions is just good business. Happy hunting! 

*Not all of these are free. Some require a purchase to read the entire study. All have free access to its abstract. That should work to give insight on the findings.

CBD Research Archive

CBD Research on: Anti-Inflammatory

Cannabidiol—transdermal delivery and anti-inflammatory effect in a murine model

Featured Quote: “In conclusion, ethosomes enable CBD’s skin permeation and its accumulation in a depot at levels that demonstrate the potential of transdermal CBD to be used as an anti-inflammatory treatment.”

The nonpsychoactive cannabis constituent cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis

A. M. Malfait, R. Gallily, P. F. Sumariwalla, A. S. Malik, E. Andreakos, R. Mechoulam, and M. Feldmann
PNAS August 15, 2000 97 (17) 9561-9566.

Edited by Anthony Cerami, The Kenneth S. Warren Laboratories, Tarrytown, NY, and approved June 2, 2000 (received for review March 10, 2000)

Featured Quote: Taken together, these data show that CBD, through its combined immunosuppressive and anti-inflammatory actions, has a potent anti-arthritic effect in CIA.

An Orally Active Cannabis Extract with High Content in Cannabidiol attenuates Chemically-induced Intestinal Inflammation and Hypermotility in the Mouse

Front. Pharmacol., 04 October 2016 |

Ester Pagano, Raffaele Capasso, Fabiana Piscitelli, Barbara Romano, Olga A. Parisi, Stefania Finizio, Anna Lauritano, Vincenzo Di Marzo, Angelo A. Izzo, and Francesca Borrelli

Featured Quote: “The present study reveals for the first time the ability of the CBD BDS to attenuate the severity of inflammation in the DNBS model of colitis, as well as to reduce transit in a model of inflammation-induced dysmotility.”

CBD Research on: Anxiety  

, Volume 12, Issue 4, pp 825–836| Cite as

Cannabidiol as a Potential Treatment for Anxiety Disorders

 

Featured Quote:  “We found that existing preclinical evidence strongly supports CBD as a treatment for generalized anxiety disorder, panic disorder, social anxiety disorder, obsessive–compulsive disorder, and post-traumatic stress disorder when administered acutely” “Overall, this review emphasizes the potential value and need for further study of CBD in the treatment of anxiety disorders.”

Braz J Med Biol Res, April 2006, Volume 39(4) 421-429 (Review)

Cannabidiol, a Cannabis sativaconstituent, as an antipsychotic drug

 A.W. Zuardi2, J.A.S. Crippa2, J.E.C. Hallak2, F.A. Moreira1 and F.S. Guimarães1

Featured Quote: “In conclusion, results from pre-clinical and clinical studies suggest that CBD is an effective, safe and well-tolerated alternative treatment for schizophrenic patients. Future trials of this cannabinoid in other psychotic conditions such as bipolar disorder (50) and comparative studies of its antipsychotic effects with those produced by clozapine in schizophrenic patients are clearly needed.”

CBD Research on: Epilepsy and other Neurological issues

Cannabidiol: Pharmacology and potential therapeutic role in epilepsy and other neuropsychiatric disorders

First published: 22 May 2014
Featured Quote: “Preclinical evidence for antiseizure properties and a favorable side‐effect profile support further development of CBD‐based treatments for epilepsy. Activity in models of neuronal injury, neurodegeneration, and psychiatric disease suggest that CBD may also be effective for a wide range of central nervous system disorders”
Volume 15, Issue 3, March 2016, Pages 270-278

Cannabidiol in patients with treatment-resistant epilepsy: an open-label interventional trial

Featured Quote: “Our findings suggest that cannabidiol might reduce seizure frequency and might have an adequate safety profile in children and young adults with highly treatment-resistant epilepsy.”

Publisher: Bentham Science Publishers

Neurological Aspects of Medical Use of Cannabidiol

Authors: Mannucci, Carmen; Navarra, Michele; Calapai, Fabrizio; Spagnolo, Elvira V.; Busardò, Francesco P.; Cas, Roberto D.; Ippolito, Francesca M.; Calapai, Gioacchino

Source: CNS & Neurological Disorders – Drug Targets (Formerly Current Drug Targets – CNS & Neurological Disorders), Volume 16, Number 5, 2017, pp. 541-553(13)

Focus quote: “Pre-clinical evidence largely shows that CBD can produce beneficial effects in AD, PD and MS patients, but its employment for these disorders needs further confirmation from well designed clinical studies. CBD pre-clinical demonstration of antiepileptic activity is supported by recent clinical studies in human epileptic subjects resistant to standard antiepileptic drugs showing its potential use in children and young adults affected by refractory epilepsy.”

Neurotherapeutics

, Volume 12, Issue 4, pp 699–730| Cite as

Molecular Targets of Cannabidiol in Neurological Disorders

Featured Quote: “We have identified a large number of potential molecular targets of CBD which are likely to be of direct relevance to many of the therapeutic effects of this compound reported in large number of preclinical and smaller numbers of clinical studies.”

. 2018; 9: 91.
Published online 2018 Apr 26. doi: 10.4103/sni.sni_45_18
PMCID: PMC5938896
PMID: 29770251

Review of the neurological benefits of phytocannabinoids

Joseph Maroon* and Jeff Bost
Featured Quote: “Although federal and state laws are inconsistent about the legality of cannabis production, its increasingly documented health benefits make it once again relevant in medicine. Current research indicates the phytocannabinoids have a powerful therapeutic potential in a variety of ailments primarily through their interaction with the ECS. CBD is of particular interest due to its wide-ranging capabilities and lack of side effects in a variety of neurological conditions and diseases.”

 

CBD Research on: Cancer

Journal of Molecular Medicine

, Volume 90, Issue 8, pp 925–934| Cite as

Chemopreventive effect of the non-psychotropic phytocannabinoid cannabidiol on experimental colon cancer

Featured Quote: “It is concluded that cannabidiol exerts chemopreventive effect in vivo and reduces cell proliferation through multiple mechanisms.”

British Journal of Clinical Pharmacology

Cannabidiol as potential anticancer drug

Paola Massi,1 Marta Solinas,2 Valentina Cinquina2 & Daniela Parolaro

Featured Quote: “Collectively, the non-psychoactive plant-derived cannabinoid CBD exhibits pro-apoptotic and anti-proliferative actions in different types of tumours and may also exert anti-migratory, anti-invasive, anti-metastatic and perhaps anti-angiogenic properties. On the basis of these results, Cannabidiol and cancer evidence is emerging to suggest that CBD is a potent inhibitor of both cancer growth and spread.”

Plant-Derived Cannabidiol on Prostate Cancer Cell Lines. Pharmacology & Pharmacy, 5, 806-820.

In Vitro Anticancer Activity of Plant-Derived Cannabidiol on Prostate Cancer Cell Lines

Manju Sharma1*, James B. Hudson2, Hans Adomat1, Emma Guns1, Michael E. Cox1,3

Pharmacology & Pharmacy, 2014, 5, 806-820
Published Online July 2014 in SciRes. http://www.scirp.org/journal/pp

Featured Quote: “Our overall findings support the concept that cannabidiol, which lacks psychotropic activity, may possess anti-inflammatory property and down regulates both cannabinoid receptors, PSA, VEGF, IL-6 and IL-8. High CBD cannabis extracts are cytotoxic to androgen responsive LNCaP cells and may effectively inhibit spheroid formation in cancer stem cells. This activity may contribute to its anticancer and chemosensitizing effect against prostate cancer. Cannabidiol and other non-habit forming cannabinoids could be used as novel therapeutic agents for the treatment of prostate cancer.”

CBD Research on: Other Health-Related topics 

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One last paper

If after all of that you would still like more information on CBD and it’s possible health benefits just click the image below. It will direct you to a very long but VERRY informative systematic review. I can not offer quotes to it since it is locked down by a sever copywriter. That being said it’s worth the read if you want to be informed on the possible benefits of CBD.

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